29 Mar 2018

NSAİDs Steroid Olmayan Antiinflamatuar İlaçlar Aplikasyonu

LC-MS/MS Methods For Veterinary Applications
Determination of the Selected NSAİDs (non steroidal anti inflammatory drugs) in milk, egg and tissue samples,
(using the Varian 320 MS Tandem Gold Triple Quadrupole LC-MS/MS System)
İNTRODUCTİON:
NSAİDs :
Nonsteroidal anti-inflammatory drugs, or NSAIDs (pronounced en-saids), are the most prescribed medications for treating conditions such as arthritis. NSAIDs are more than just pain relievers. They also help reduce inflammation and lower fevers. They prevent blood from clotting, which is good in some cases but not so beneficial in others.
NSAIDs are frequently used to treat inflammatory conditions such as arthritis, bursitis and tendonitis. NSAIDs are relatively inexpensive and are frequently the first line of medication used to relieve pain and reduce inflammation.
List of NSAİDs in method :
Diclofenac, Meloxicam, Acetylsalicylic acid (Salycilic Acid as biomarker), Phenylbutazone, 4-Hydroxy Flunixin, 4-MAA(4-Methylamino antrypine), Tolfenamic acid, Carprofen, Flunixin.
Method Details:
LC Conditions:
Gradient elution was used with 0,25 ml/min flow rate.
İnjection Volume : 30 ul
Run time: 16 min
Column Oven : Room Temperature
Analytical Column: Dikma İnspire C18, 100*2,1 , 3 um
 
Please contact for the rest of method…